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Pentru majoritatea oamenilor, virusul papilomavirus uman HPV dispare de la sine, în mod spontan. Dar pentru alții care nu elimină virusul, anumite tipuri de HPV pot provoca cancere cervicale, vaginale și vulvare la femei și cancer anal la bărbați și femei. Alte tipuri pot provoca veruci genitale atât la bărbați, cât și la femei. Infecția cu acest virus este comună.

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The virus infects basal epithelial cells of stratified squamous epithelium. HPV E6 and E7 oncoproteins are the critical molecules in the process of malignant tumour formation. Interacting with various cellular proteins, E6 and E7 influence fundamental cellular functions like cell cycle regulation, telomere maintenance, susceptibility to apoptosis, intercellular adhesion and regulation of immune responses. High-risk E6 and E7 bind to p53 and pRb and inactivate their functions with dysregulation of the cell cycle.

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Cervarix nu protejează persoanele de boala determinată de infecţia cu HPV 16 sau 18 dacă acestea sunt deja infectate cu papilomavirusul uman de tip 16 sau 18 la momentul vaccinării. Cervarix does not protect people from diseases caused by infection with HPV types 16 or 18 if they are already infected with Human Papillomavirus type 16 or 18 at the time of vaccination. Negii sunt excrescenţe ale pielii şi mucoasei cauzate de papilomavirusul uman HPV.

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Просто не верилось, что туннель этот проложен где-то в глубочайших недрах города. Искусство, пользовавшееся Диаспаром как одним огромным холстом, проникло и сюда, и им казалось, это небо над ними распахнуто навстречу райски ароматным и свежим ветрам.

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Через какие-то считанные минуты трансформация завершилась. Не осталось ни одного кусочка величиной более дюйма. А вода кишела крохотными зеленоватыми точками, которые, казалось, жили и двигались по своему собственному разумению и быстро исчезали в пространстве озера.

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