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Infecţiile cu tulpini HPV cu risc scăzut sunt asociate în mod caracteristic cu verucile genitale condiloamele, negii din zona genital. Tulpinile HPV cu risc crescut sunt responsabile de apariţia cancerului de col uterin. De aceea e important de înţeles că nu orice infecţie cu HPV poate duce la cancer de col uterin.

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Acesta sta la baza majoritatii neoplaziilor cervicale, dar si intr-un procent mai scazut al celor vulvare, anale si din zona gatului. Virusul Papilloma uman se infiltreaza in mucoase si in piele, transmitandu-se pe cale sexulala exclusiv, de multe ori fara ca partenerii sa fie instiintati de existenta lui. Aceasta infectie nu prezinta simptomatologie asociata. Exista aproximativ de tipuri si subtipuri de HPV diferite genetic.

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Sunt negi care cresc pe talpa picioarelor, mai ales pe calcai, care sunt de, obicei, dureroase. Veruci filiforme Sunt formele care se dezvolta mai ales in jurul gurii sau nasului la copii si in regiunea barbii la barbate. Pot apare, de asemnea pe gat, sub barbie.