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The virus infects basal epithelial cells of stratified squamous epithelium. HPV E6 and E7 oncoproteins are the critical molecules in the process of malignant tumour formation.

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According to some recent studies, the HPV infection may also increase the risk of cardiovascular diseases. Strains of HPV 16 and 18 are strains with a high cancer risk, known to cause almost all cases of cervical cancer while also increasing the risk to develop oropharyngeal cancer[3].

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