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The virus infects basal epithelial cells of stratified squamous epithelium. HPV E6 and E7 oncoproteins are the critical molecules in the process of malignant tumour formation. Interacting with various cellular proteins, E6 and E7 influence fundamental cellular functions like cell cycle regulation, telomere maintenance, susceptibility to apoptosis, intercellular adhesion and regulation of immune responses. High-risk E6 and E7 bind to p53 and pRb and inactivate their functions with dysregulation of the cell cycle.

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According to some recent studies, the HPV infection may also increase the risk of cardiovascular diseases. Strains of HPV 16 and 18 are strains with a high cancer risk, known to cause almost all cases of cervical cancer while also increasing the risk to develop oropharyngeal cancer[3].

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Я видел мир совсем без жизни и мир, где жизни слишком много - и не знаю, который из них мне более неприятен. Когда путешественники достигли двухкилометровой высоты, планета напоследок удивила их еще .

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Тысячи и тысячи их уже бежали в короткое забытье Хранилищ Памяти в надежде, что, когда они снова пробудятся, нынешний кризис будет уже преодолен и Диаспар снова станет самим собой, таким знакомым и привычным. Что поделать -- их ожидало разочарование.

Джизирака кооптировали на одно из образовавшихся вакантных мест в составе Совета.

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Впрочем, он был далек от мысли протестовать по этому Свет, исходивший от металлической груши наверху, померк до слабого сияния, но излучаемое ею тепло не убывало. В последних проблесках света затуманившийся рассудок Элвина отметил курьезное обстоятельство, о котором обязательно следовало расспросить наутро.